Amazing Spider-Man (1963) #43

3rd appearance & origin of Rhino (Aleksei Sytsevich)

"Rhino on the Rampage!"

The Rhino’s tranquilizer wears off and he begins another escape from jail seeking out Spider-Man. At the Daily Bugle, Ned Leeds and Betty Brant announce their engagement, but the scene changes to Peter Parker being enamored by Mary Jane at home. A TV bulletin interrupts and announces The Rhino’s escape. Peter realizes Spider-Man must confront him and Mary Jane suggests they go downtown to watch the action.