Amazing Spider-Man (1963) #300 CGC 5.0

1st full appearance & origin of Venom (Eddie Brock)

Return of Spider-Man's iconic red and blue costume

"Venom"

Spidey's old alien costume has merged with reporter Eddie Brock who thinks his career was ruined by Spider-Man and the symbiote of the two, Venom, takes on the web slinger. At MJ's request, Spidey returns to the blue and red costume as she now finds his black duds way too creepy.

"Stan's Soapbox Special" – A full-page editorial by Stan Lee on the occasion of Spider-Man's 300th issue.